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Newton resident Benjamin Wolozin, MD, PhD, a professor of pharmacology at Boston University School of Medicine, was one of nine Massachusetts researchers to receive a 2007 Memory Ride Grant from the Alzheimer’s Association. Wolozin received a three-year investigator-initiated research grant for nearly $240,000 to study LRRK2 interactions with pathways linked to protein folding and degradation.The LRRK2 gene provides instructions for making a protein called dardarin. [click link for full article]

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George Mason University professor of psychology, Raja Parasuraman, has received a $2.6 million grant from the National Institutes of Health to conduct research regarding the detection and prevention of Alzheimer’s disease. His program, “Apolipoprotein, Attention and Alzheimer’s disease,” will annually test more than 500 middle-aged and older adults for four years using cognitive, genetic and magnetic resonance imaging (MRI) tests to identify precursors of Alzheimer’s disease. [click link for full article]

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A Mediterranean diet may help people with Alzheimer’s disease live longer than patients who eat a more traditional Western diet. The study is published in the September 11, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. The study followed 192 people with Alzheimer’s disease in New York for an average of four and a half years. During that time, 85 of the people died. [click link for full article]

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Researchers using functional magnetic resonance imaging (fMRI) have found a new marker which may aid in early diagnosis of Alzheimer’s disease, according to a study published in the October issue of Radiology.”The findings of this study implicate a potential functional, rather than structural, brain marker — separate from atrophy — that may help enhance diagnosis and treatment monitoring of Alzheimer’s patients,” said the study’s lead author, Jeffrey R. Petrella, M.D. [click link for full article]

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Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer’s memory loss could be due to a novel third form of diabetes.Now scientists at Northwestern University have discovered why brain insulin signaling — crucial for memory formation — would stop working in Alzheimer’s disease. [click link for full article]

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The Alzheimer’s Society has announced that it will not appeal the recent high court judgment on access to Alzheimer’s drugs.Last month, a high court judge, Mrs Justice Dobbs, ruled that the National Institute for Health and Clinical Excellence’s (NICE) guidance on prescribing drugs to people with Alzheimer’s disease on the NHS breached disability and race discrimination law. The public body was ordered to make changes to its guidance. [click link for full article]

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An HIV patient whose platelet counts (the number of clotting cells in the blood) are declining is probably more likely to suffer from HIV-associated dementia, says an article in Archives of Neurology (JAMA/Archives), September issue. [click link for full article]

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A new study led by investigators from the University of Pittsburgh School of Medicine demonstrates that the process of necrosis, long thought to be a chaotic, irreversible pathway to cell death, may actually be triggered as part of a regulated response to stress by a powerful protein, SRP-6, that can potentially halt necrosis in its path. [click link for full article]

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With an estimated 700,000 people in the UK suffering from some form of dementia and an ageing UK population, a new YouGov survey highlights a lack of public awareness regarding Alzheimer’s disease and dementia. When respondents were asked how well informed they are about the early symptoms of Alzheimer’s disease or dementia, 66% were either not very well informed or not informed at all. Only 5% considered themselves very well informed1. [click link for full article]

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Researchers have found surprising evidence that an antidepressant (citalopram) may perform as well as a commonly-prescribed antipsychotic (risperidone) in the alleviation of severe agitation and psychotic symptoms of dementia. Researchers also found that the antidepressant was associated with “significantly lower” adverse side effects. [click link for full article]

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