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An international group of scientists found that a new gene called calcium homeostasis modulator 1 (CALHM1), with a previously unknown function, is linked to late-onset Alzheimer’s Disease making this the second discovery of a strong genetic risk factor for the disease.

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The New York Times on Tuesday examined the growing use of antipsychotic drugs to lessen “the agitation, combative behavior and outbursts” of dementia patients. Sales of newer antipsychotics — including Risperdal, Seroquel and Zyprexa — increased from $4 billion in 2000 to $13.1 billion in 2007.

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Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively “puts the brakes” on the dementia that comes with Alzheimer’s disease (AD). When the brakes fail, dementia results.This discovery could open the door to new ways of treating Alzheimer’s disease, which affects up to half the population over the age of 85.

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Brain destruction in Alzheimer’s disease is caused by the build-up of a protein called amyloid beta in the brain, which triggers damaging inflammation and the destruction of nerve cells. Scientists had previously shown that preventing individual amyloid beta proteins from sticking to one another minimized brain lesions and protected nerve cells against damage.

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Standard neurological exams of older adults are good predictors of future brain health and quality of life. These tests should become part of the physician’s routine examination of older adults say faculty from the Indiana University Center for Aging Research in an editorial in the June 23, 2008 issue of the Archives of Internal Medicine.

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Pfizer Inc invites investors, media, and the general public to view and listen to a webcast of a presentation by Pfizer’s neuroscience leadership team at an analyst and investor meeting on Monday, July 28, at 6:00 p.m. Central Daylight Saving Time, in connection with the annual meeting of the International Conference on Alzheimer’s Disease (ICAD). To view and listen to the webcast, visit our web site homepage at

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An automated system for measuring brain tissue with magnetic resonance imaging (MRI) can help physicians more accurately diagnose Alzheimer’s disease at an earlier stage according to a new study published in the July issue of the journal Radiology.In Alzheimer’s disease, nerve cell death and tissue loss cause all areas of the brain, especially the hippocampus region, to shrink.

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Scientists have long questioned whether the abundant amounts of amyloid plaques found in the brains of patients with Alzheimer’s actually caused the neurological disease or were a by-product of its progress. Now, using new research techniques, scientists have shown that a two-molecule aggregate (or dimer) of beta-amyloid protein fragments may play a role in initiating the disease.

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Alzheimer Scotland launched its brand new fundraising campaign, Care for a curry™, in Glasgow on Monday night with a fantastic evening of curry and comedy at the famous Stand comedy club, raising a great total of £1100. Stand-up from Raymond Mearns, Andy Sir, Scott Agnew and Elaine Malcolmson (compered by the incomparable Billy Kirkwood) provided plenty of laughs while a fantastic spread from the nearby Shish Mahal restaurant gave attendees plenty to get their laughing gear around.

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Alzheimer’s Australia today, released a report ‘Australian Dementia Research’ that recommends annual funding for dementia research be increased three-fold to $36 million in response to the growing economic and social impact of the dementia epidemic.Prepared by the Dementia Collaborative Research Centre at the University of NSW, the report concludes that current investment over the last six years in dementia research was about $13 million, 0.

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