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Alzheimer’s Society comment: Living with a partner in midlife can reduce your risk of dementia, according to new research presented at the International Conference on Alzheimer’s Disease. ‘Some evidence suggests remaining socially active may reduce your risk of dementia and living with someone is certainly a good way of increasing social interaction.

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Eisai Inc. and Pfizer Inc (NYSE: PFE) announced results from a new open-label study that showed Hispanics with mild to moderate Alzheimer’s disease (AD) experienced significant improvement in cognition compared to baseline after 12 weeks of treatment with ARICEPT. This is the first clinical trial looking at an AD prescription medication exclusively in Hispanics, and is important given the high risk of AD among this large population.

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New results announced at the International Congress on Alzheimer’s disease (ICAD) in Chicago indicate that a medical nutrition product (SouvenaidTM) may offer a new option in the management of people with mild Alzheimer’s disease.

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Medivation, Inc. (NASDAQ: MDVN) announced new data showing that its investigational drug Dimebon continues to produce broad, clinically meaningful benefits in Alzheimer’s disease patients after long-term dosing, and appears to operate through a novel mechanism of action. These data were presented recently in a podium session and two poster sessions at the 2008 Alzheimer’s Association International Conference on Alzheimer’s Disease (ICAD) in Chicago.

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Elan Corporation, plc (NYSE: ELN) and Wyeth (NYSE: WYE) are presenting detailed results from the companies’ 18-month Phase 2 study of bapineuzumab (AAB-001) in patients with mild to moderate Alzheimer’s disease at the Alzheimer’s Association’s International Conference on Alzheimer’s Disease 2008 in Chicago, Illinois. As previously announced, in the study, bapineuzumab appeared to have an acceptable safety profile and clinical activity in treating Alzheimer’s disease.

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Medical College of Wisconsin researchers in Milwaukee have reported that children of Alzheimer’s patients who are carriers of a genetic risk factor for Alzheimer’s disease have neurological changes that are detectable long before clinical symptoms may appear.

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GE Healthcare, a unit of the General Electric Company (NYSE:GE), announced positive results from a Phase I clinical trial of GE-067, a [18F]-labeled PET diagnostic imaging agent being developed by the company to assist in the detection of brain beta-amyloid.

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A new study suggests that those who are unmarried or not living with a partner in midlife could have an increased risk of developing Alzheimer’s disease, according to research reported today at the 2008 Alzheimer’s Association International Conference on Alzheimer’s Disease (ICAD 2008), in Chicago.

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Eli Lilly and Company (NYSE: LLY) announced interim results of its Phase II study of LY2062430, an investigational anti-amyloid beta monoclonal antibody for the treatment of mild to moderate Alzheimer’s disease. In this study, intravenously administered LY2062430 bound to the amyloid beta protein, resulting in increased amounts of amyloid beta in participants’ blood and cerebrospinal fluid.

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An overwhelming number of Americans with memory concerns fail to report this health issue with their doctors despite visits within the past six months, according to results released today of a survey of participants in the Alzheimer’s Foundation of America (AFA) National Memory Screening Day last November. AFA announced the results at a poster session at the Alzheimer’s Association’s 11th International Conference on Alzheimer’s Disease in Chicago.

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