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Alzheimer’s Society comment on the infra-red helmet trialled by Sir Terry Pratchett in the forthcoming BBC Two documentary. Manufacturers claim the helmet improves cognition in people with dementia. ‘We welcome any new initiatives to help fight dementia, but the infra-red helmet is still at an early stage of research. We need a proper clinical trial to determine whether or not it is a safe and effective treatment for people with dementia.

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First there were 7,000 purple postcards calling for a state Alzheimer’s plan, sent continuously over the past few months to Governor Deval Patrick. He has not yet responded.

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A new report published by Biopharm Reports in Jan 2009 brings together the latest advances in the identification of biomarkers in Alzheimer’s disease. It is hoped that these discoveries will provide new opportunities to tackle this disease, from research through to the clinic.

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A sub-study of a trial looking at the effect of diabetes on heart disease risk found that higher levels of hemoglobin A1C levels (a measure of a person’s average blood glucose over a 2 to 3 month period) were linked to lower cognitive function.

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Research undertaken by the British Geriatrics Society on behalf of Help the Aged has revealed that 47% of doctors specialising in the care of older people think the NHS is institutionally ageist. 77% of doctors would support the introduction of legislation against age discrimination in the NHS. The research also revealed that 66% agreed that, in their experience, older people are less likely to have symptoms fully investigated.

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1. Mutated LRRK2 Activates Cell Death Pathways Cherry Cheng-Ying Ho, Hardy J. Rideout, Elena Ribe, Carol M. Troy, and William T. Dauer Among the few familial forms of Parkinson’s disease (PD), the most commonly mutated gene is leucine-rich repeat kinase 2 (LRRK2). Based on its subcellular localization, interaction partners, and homologies with other proteins, LRRK2 is thought to play a role in membrane trafficking; but how LRRK2 mutations lead to PD is unknown.

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Leading medical experts at the Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine (BUSM) reported today that nine-year NFL veteran, former Tampa Bay Buccaneer Tom McHale was suffering from chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by head trauma, when he died in 2008 at the age of 45.

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Researchers have found the first evidence that athletes who were concussed during their earlier sporting life show a decline in their mental and physical processes more than 30 years later. The research, published online today (Wednesday 28 January) in one of the world’s leading neurology journals, Brain [1], compared 19 healthy, former athletes who had sustained concussion more than 30 years ago with 21 healthy, former athletes with no history of concussion.

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Diabetics have a significantly greater risk of dementia, both Alzheimer’s disease the most common form of dementia and other dementia, reveals important new data from an ongoing study of twins. The risk of dementia is especially strong if the onset of diabetes occurs in middle age, according to the study. “Our results . . . highlighted the need to maintain a healthy lifestyle during adulthood in order to reduce the risk of dementia late in life,” explained Dr.

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A study published in Journal of the American Geriatrics Society suggested that the use of certain medications in elderly populations may be associated with cognitive decline. The study examined the effects of exposure to anticholinergic medications, a type of drug used to treat a variety of disorders that include respiratory and gastrointestinal problems, on over 500 relatively healthy men aged 65 years or older with high blood pressure.

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